Buenos Aires: Editorial El Ateneo, ; cap. Desarrollo pulmonar. Fetal lung maturity. American College of Obstetricians and Gynecologist. Obstet Gynecol ; Am J Clin Pathol ;
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Los fosfogliceridos lecitinas y la esfingomielina forman el grupo de fosfolipidos involucrados. En el neumocito II, enzimas remodelan las diferentes lecitinas para convertirlas en dipalmitoil fosfatidil colina.
Menos de un 0. Abstract Pulmonary surfactant is a tensoactive substance produced by type II pneumocytes. The remainder are surfactant proteins. Phosphoglycerides lecithins and sphyngomyelin are involved phospholipids. Most abundant lecithins in extracelular fluid covering normal pulmonary alveoli are phosphatydil-choline and dipalmitoil phosphatydil choline, and in pulmonary surfactant that decreases surface tension as well.
Thus, atelectasis at the end of expiratory phase is avoided. Type II pneumocytes contain a number of enzymes that remodel different lecithins to transform them in dipalmitoil phosphatydil choline. Corticoid administration enhances lung maturity in at risk cases of pre-term delivery, or when acesarean sections is indicated as soon as possible, before term. Premature babies having the idiopathic respiratory distress syndrome are treated with surfactant administration into the tracheobronchial tree.
There are other tests designed to meet this task, like measurement of lamellar bodies. This test can be trusted, is cheaper is readily available in less sophisticated hospitals and medical centers.
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